Longevity & Mitochondria
Mots-c
Mitochondrial Peptide
$65.00
Size
15 in stock · 10 mg per vial
Description
Mitochondria-derived peptide. Studied for its role in metabolic regulation, insulin sensitivity, and cellular energy homeostasis.
Research
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondria-derived peptide encoded within the mitochondrial genome. Research has identified it as a key regulator of metabolic homeostasis, acting as a mitochondrial hormone that translocates to the nucleus under metabolic stress. Preclinical studies show MOTS-c improves insulin sensitivity, reduces diet-induced obesity, and enhances exercise capacity in animal models. Mechanistic research indicates it activates AMPK signaling and regulates the folate cycle and de novo purine synthesis. Studies also suggest MOTS-c levels decline with age, positioning it as a subject of longevity and age-related metabolic dysfunction research. All findings are from preclinical models.
RESEARCH USE ONLY. Not for human or veterinary consumption. This product is sold to qualified researchers aged 21 or older for laboratory research purposes.